抄録
Recently, mechanical cardiac assist devices are applied for the incurable cardiogenic shock patients---that are LVAD, BVAD and TAH.
New designed cardiac assist device---sac type of Avcothane-coated PVC blood pumps and driving units controlled by microprocessor---was developed. The candidates of LVAD and BVAD are estimated approximately 2, 000 per year in Japan.
Since 1959, TAH animal experiments was started in Tokyo University and 288 days survival of TAH goat was obtained.
Until now, 11 TAH animal survived over 6 months in the world and their death are pannus formation, clotting, infection and pump repture.
The candidates of TAH are estimated about 4, 000 per year in Japan.
In future, movable (wheel-chair type) or implantable TAH will be developed for the clinical use.
