人工臓器
Online ISSN : 1883-6097
Print ISSN : 0300-0818
ISSN-L : 0300-0818
Electrolyte transport across the dialyzer's membrane: A preliminary study of the Donnan equilibrium
K. TOTSUNE
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1988 年 17 巻 1 号 p. 69-72

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In order to obtain the formula to calculate the Donnan ratio (R) from protein concentration in plasma (Ctp) and sodium concentration in dialysate (D[Na]), the experimental equilibrium dialyses were performed in vitro. The formula was represented as follows:
R=1.0-αR×Ctp/D[Na] where αR is a constant.
The values of αR varied with the measurement methods for Na and Cl. The results indicated that when the Donnan equilibrium phenomenon was discussed, Na concentrations measured by flamephotometry and Cl by potentiometric titration should be used after the correction as to the complex-binding to albumin, and also suggested that Na and Cl concentrations by Ion-Selective Electrode should be carefully dealt with.
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© The Japanese Society for Artificial Organs
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