抄録
Improvement of the prototype of bilateralpulsatile closed-circuit cardiopulmonary bypass system was achieved. In animal experiments of goat by prototype, it was thought that it would be neccessary to achieve much perfusion flow, less priming volume and smaller machine size. In order to find out the factor which reduced perfusion flow, we analysed the hidrodynamical caracteristics of our system and it was revealed the main factors were venous and arterial cannulae. in order to use bigger and shorter connectiot tube, putting all part but membrane oxygenator and heat exchanger in the sterized area, we could priming volume less than 1300ml and get perfusion flow of 5L/min. with one of 6mm arterial cannula and two of 6mm cannulae.