Cross Resistance of Staphylococcus aureus to Streptomycin and Kanamycin
1966 Volume 21 Issue 2 Pages 120-123
Details
1966 Volume 21 Issue 2 Pages 120-123
The cross resistance of one-step highly streptomycin (SM) resistant mutants and SM dependent mutants against kanamycin (KM), and the genetics of the cross resistance were reported previously in Escherichia coil strain B/r.
The present author attempted to analyse the genetics of the cross resistance using SM dependent mutants of Staphylococcus aureus.
Analytical experiment using transduction technique did not show any positive result.
However, the results of exact observation in Staphylococcus aureus strain 209P suggested that the same genetic mechanism concerned as in the case of Esherichia coil with regard to SM resistant mutants and SM dependent mutants, and that non-dependent mutants derived from SM dependent mutants were also suppressor mutants.
