熱測定
Online ISSN : 1884-1899
Print ISSN : 0386-2615
ISSN-L : 0386-2615
解説
ガラス性医薬品の分子運動性
川上 亘作
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ジャーナル フリー

2008 年 35 巻 4 号 p. 185-191

詳細
抄録
Although use of glassy state for pharmaceutical formulations is not a new idea, it is recognized again as a promising formulation technology to enhance dissolution rate due to increase in poorly soluble candidates. However, because of its low physical/chemical stability and difficulty in industrial manufacturing, number of commercialized formulations has still been limited. In this review, molecular mobility of glassy pharmaceuticals is introduced with great emphasis on its effect on the physical/chemical stability.
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© 2008 日本熱測定学会
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