熱測定
Online ISSN : 1884-1899
Print ISSN : 0386-2615
ISSN-L : 0386-2615
解説
熱測定を利用した医薬品化合物の 結晶/非晶質物理状態評価
川上 亘作
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ジャーナル フリー

2010 年 37 巻 1 号 p. 2-8

詳細
抄録
Molecular conformation/arrangement of active pharmaceutical ingredients and excipients in the solid state has great impact on physicochemical characteristics of the formulations including solubility and stability. Although various methodologies are available for their investigation, thermal analysis has great advantages in terms of its high sensitivity and flexibility. In this paper, thermal analysis for the evaluation of polymorphism and amorphous state is described from practical viewpoint in the pharmaceutical industry.
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© 2010 日本熱測定学会
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