抄録
Micronuclei (MN) and other nuclear abnormalities (NA) formation were confirmed in the peripheral erythrocytes of the red sea bream, Pagrus major, exposed to water- and diet-borne polycyclic aromatic hydrocarbons (PAHs). Their frequencies were significantly different from controls, with highest ∑MN&NA frequencies of 7.18 and 18.1 per 1000 erythrocytes in the water- and diet-borne exposures respectively, against highest water and dietary controls frequencies of 0.67 and 2.30 per 1000 erythrocytes respectively. ∑MN&NA persisted in the depuration period, and their frequencies varied directly with tissue ∑4PAH concentrations.
These biomarkers can be used in the red sea bream for PAH biomonitoring.
