2018 Volume 39 Issue 2 Pages 131-136
To clarify the benefits and risks of no-down-time, low-fluence treatment with picosecond lasers, this study evaluated 217 patients who underwent treatment in a single clinic. All treatments were performed by a single physician using a standard picosecond alexandrite laser. Photographs taken before every treatment were evaluated. This study revealed that low-fluence picosecond alexandrite laser treatment is very effective for freckles and moderately effective for solar lentigines, but ineffective and possibly dangerous for melasma because more than 5% of all patients showed worsening of symptoms.