エキシマレーザーを用いたLaser Angioplasty

抄録

We carried out a study on the possible application of the excimer laser in laser angioplasty. In the first experiment, the ablative effects of the excimer laser at the wavelengths of 248 nm (KrF) and 308 nm (XeCl) on the pig myocardium were examined in vitro at an air-tissue interface. Very clear cuts were observed on the histological examination. There was no evidence of thermal damage. In the second experiment, the excimer laser was coupled to a 400 μm quartz optical fiber. Laser angioplasty was performed in 4 totally occluded femoral arteries in mongrel dogs using the excimer laser (XeCl: 308 nm). The arteries were successfully recanalized in all 4 arteries using 2.5-6 mJ/pulse, 20-30 pps and 6000 shots.