各種レーザー照射による皮膚組織への影響

抄録

Light and electron microscopic findings of benign cutaneous pigmented lesions irradiated with several types of laser were reported, and their cause of clinical limitation were discussed. In port-wine stain, hyperpigmentation of epidermis, extensively dilated vessels, small amount of red blood cells in the vessels and deeply located vessels were considered to be main causes which the effects of dye laser fade away. Epidermal melanin pigmentation was removed with laser treatment, but the amount of the pigment in the repaired epidermis seems controlled genetically. Dermal melanocytes in nevus of Ota showed destruction with melanosomes disruption by Q-switched ruby and alexandrite laser irradiation, but long term follow up study is not made yet.