1995 年 16 巻 Supplement 号 p. 293-294
We have treated about two hundreds cases of Nevus Ohta and sixty cases of ectopic mongorian spots.
Dosages of laser was 6J/cm2 Interval of treatments was more than six weeks. Q-switched ruby laser was effective in all cases. However, repeated treatment was necessary, pigmentation improved after three times laser irradiation. At least five times irradiation was necessary to show dramatical improvement in adult. In children, three times laser irradiation was enough to achieve good results in almost cases. This might related to the fact that children's skin was thinner than adult's skin.
Histological examination by using KP-1 antibody suggested that the peak of macrophage activity exist within two months after laser irradiation.