We analyzed the results of endoscopic mucosal resection (EMR) for early gastric cancer and of laser irradiation to the residuals after EMR. Between 1986 and April 1997, 248 lesions were performed EMR, in those 154 lesions were classified in a absolute indication group, 94 lesions in a relative indication group. In them 71 lesions were treated by a laser irradiation as a additional therapy after EMR. The curative rate of EMR was over 70% for lesions below 10 mm in size, and less than 50% for the size over 11 mm. The cure rate of EMR was 66.9% (103/154) for an absolute indication group and 39.4% (37/94) for a relative indication group.The cure rate of laser irradiation for the residual tumor after EMR was raised to 95.5% in the absolute indication group (n=44) and 70.4% in the relative indication group (n=27). Combination therapy of EMR and laser irradiation is a useful treatment to avoid a invasive treatment as operation for limited patients.
