Newly developed excimer dye laser system for cancer diagnosis and treatment was evaluated clinically. Diagnosis and treatment were performed photodynamically after the administration of HpD. Five patients with lung cancer consisting of four cases of squamous cell carcinoma and a single case of adenocarcinoma showed HpD-specific fluorescenc at the lesions. In the treatment, 50-140 joules/cm2 photoradiation were administered to the lesions. All lesions showed significant remission. A case of early stage squamous cell carcinoma of the right upper lobe bronchus showed complete remission and is now disease free at 11 months. This system is more effective in the diagnosis and treatment than previous procedures.
