昭和医学会雑誌
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
日本に於ける流行性耳下腺炎のウイルス学的研究 (四) (流行性耳下腺炎のウイルス分離に関する研究)
福留 勇鈴木 茂坪井 秀文内村 良二中沢 進
著者情報
ジャーナル フリー

1956 年 16 巻 4 号 p. 321-328

詳細
抄録
Fertilized eggs of white leghorn were inoculated into amniotic cavity with the saliva collected from 15 cases of mumps. Two strains of mumps virus were isolated as the results. The virus was proved by hemagglutination first at 4 th or 5 th generation of passage. Chick erythrocyte agglutination titre of the virus was not determined at the first positive generation. It was 640 at 2 nd generation. It became lower during the period from 9 th to 15 th generation, and later showed the maximal titre of 3840. Thereafter, the titre remained between 320-1280. As the virus was accidnetally proved during the passages, the connection between the virus inoculated and that recovered was not clear. However, the findings in the separate experiments on the recovery of the virus was found explaining, the above connection. Since the isolation of the virus was successful only in 2 cases, discessions were made on the remaining 13 cases from the view point of the presence or absence of the virus. As the results, the ahthors stated that the success or failure in the isolation of the virus should not be judged only from the amount of the virus. When observed from the readiness for the so-called adaptation to the egg, these 2 isolated strains did not show the readiness for the adaptation. In other words, these 2 strains became readily adaptable by mere accident. Therefore, the many negative results obtained in the present word was considered not unreasonable even if the virus would have been Present. These 2 strains of virus were presumed to be mumps virus from the results obtained in the separate immunological experiments and in the studies on the experimental human mumps.
著者関連情報
© 昭和医学会
前の記事 次の記事
feedback
Top