胃粘膜腸上皮化生に関する病理組織学的研究

抄録

1. Intestinal epitherial metaplasia was observed on the gastric mucoua at the portion of pyloric antrum in 60%, namely, 30 out of 50 cases examined.
2. In regard to the Paneth cell, which is observed on the metaplastic intestinal epithelium descriptions were made that it sometimes shows atypical appearance, that it is the clue to show the relationship of intestinal epitherial metaplasia and mucoid gland, or that it is the indication of active metaplasia, and further that it appears to be closely related with the bifurcation of intestinal epithelial metaplasia.
3. The intestinal epitherial metaplasia was divided into duodenal type, jejunal type, ileal type and colonic type on the basis of the presence of mucoid gland and Paneth cell.
4. Cells of the pyloric gland, Brunner's gland, pseudo-pyloric gland, pseudo-Brunner's gland and the accesory cells of the f undus gland were found th show identical charcteristics on varying staining tests. Since the content of those cells, moreover, gave the characteristics of mucoid substance, it is proposed to call the glands formed by those cells as mucoid glands.
5. Attention was invited to the fact the stained samples of pseudopyloric gland gave considerably different pictures depending on the section examined.
6. Descriptions were mad that shapes of pseudo-pyloric gland is variant and, in and extreme case, it was seen as the mere grouping of a few mucoid cells at the base of the metaplastic intestinal epithelium being deficient of any lumen.
7. A proof was given on the possibility of the connection of mucoid gland located under the mucous muscle seemingly left over by the follow-up made with serial sections.
8. Development of the pseudo-pyloric gland was shown to be closely related wit the metaplasia of accessory cell.