腎代償性肥大に関する研究 (実験的研究)

抄録

1. On measuring various parts of the body of white male rats of Wistar breed, the ratio of renal weight to the body weight was found to decrease repidly as far as 55 days after birth, and gradually being eased thereafter. Its ratio to the body length was found to increase gradually while its ratio to the bcdy surface area remained always constant.
2. No difference in the measurement was recognized between the kidney of right side and the left side. An extremely high grade of positive correlation was found to exist among the renal weight, long axis, width and the thickness. Extirpation of one side kidney, therefore, was sufficient for measurement.
3. Compensatory renal hypertrophy appears to be completed within a relatively short pericd of time and the rate of renal hypertrophy observed on the rat 30 days after birth followed a rapid increase as far as 40 days after operation reaching to the maximum rate of 2.14 times, and this increase slackened thereafter. The ratio of the hypertrophied kidney to the body surface area attained the maximum rate of 2.92 on the 40th day after operation and diminished thereafter.
4. On experimentally hypertrophied kidney, the ratio of width to the long axis, the ratio of thickness to the long axis, and the ratio of thickness to the width all presented a remarkable increase as far as 40 days after operation and the ratios decreased gradually thereafter. The rate of elongation was highest in the thickness, and the width and the long axis followed in the order listed, the kidney gradually becoming spherical.