The authoo found that when kanamycin was used in the treatment of epidemic paratitis, its translocation into the saliva is increased in case of the child who has inflammation in the salivary gland. To investigate whether this phenomenon is due to inflammation or general infection, the author induced various general infections and local inflammations in rabbits, than administered Ampicillin (AB-PC) or Cephaloridine (CER) to them, and examined its translocation by determining the concentration in parotid saliva, mixed saliva, accumulated saliva and blood, obtaining the results reported in this paper.