抄録
Zonal necrosis frequently occurs when the liver is subjected to a severe toxic stress. Though coagulation necrosis usually occurs under such circumstances, colliquative necrosis in a small number of cases should not be overlooked. A pathological study was therefore undertaken on the process in the liver from colliquative changes to colliquative necrosis in-duced by injecting saponin and hydroxylamin hydrochloride subcutaneously in a rabbit.
Colliquative necrosis was thus produced in radiating form along the sinusoid connect-ing the central and the peripheral vein.
Such colliquative necrosis in the radiation form was probably related to hemolytic anemic hypoxemia induced by hydroxylamin and saponin.
