Abstract
The analysis of calcium (Ca) and strontium (Sr) elements in epiphyseal cartilage plate (ECP) and trabeculae of bone of rat-tibiae given SrCO3 was done by using an electron probe X-ray microanalyser (EPMA) and a laser microspectral analyser (LMA) .
In the ECP of both control and low Ca rats, both Ca and Sr elements were not found by EPMA. Ca elements were detected by LMA, but Sr elements were not detected by LMA. In the ECP of rat given SrCO3, both Ca and Sr elements were found not by EPMA but by LMA. In the trabeculae of bone of both control and low Ca rats, Ca elements were found, but Sr elements were not shown by EPMA. In the trabeculae of bone of rat given SrCO3, both Ca and Sr elements which distributed uniformly in trabeculae of bone were found by EPMA. From these facts, it was suggested that the analytical limits for some biological important elements of LMA were lower than that of EPMA, and Sr invaded epiphyseal cartilage plate and disturbed endochondral ossification.
