Abstract
Immunohistochemical staining for Ki-67 (MIB-1) and argyrophilic nucleolar organizer regions (AgNORs) was performed on paraffin-embedded sections (or speimens) from 26 testicular tumors and 20 normal testicles. The number of AgNORs in testicular tumors (6.96±1.50) was significantly higher (p<0.001) than that in normal testicle (2.62±0.42) . The Ki-67 index of testicular tumors (33.65±13.34) was significantly higher (p<0.001) than that of normal testicle (2.76±1.96) . There was no correlation between AgNORs number and Ki-67 index in testicular tumors. These findings indicate that AgNORs number and Ki-67 index are possible indicators of proliferative activity or malignancy of testicular tumors.
