抄録
The depression of skin barrier function causes that it is easy to take into various chemical substances, so that it causes allergy. It is very useful to quantitatively evaluate the state of the skin barrier in domains such as dermatology, nursing science and the cosmetics development. Therefore the authors developed a portable impedance measuring device for evaluation of skin barrier function. This device can be operated by single hand because of compact and lightweight. After the head contacts the skin, the parameters, such as susceptance B and admittance Y in two kinds of frequencies, are measured and calculated in approximately three seconds. The equivalent impedance circuitry, that represents some kinds of keratin-removing skins by tape stripping method, consisted of parallel RC circuits. Using these circuits the precision of this device were confirmed that the errors were less than several percent.The correlation with these parameters and TEWL (transepidermal water loss), and the regression expressions for estimation of TEWL were examined. We found that an index of corneum barrier about the same as TEWL.
