四分円解析を用いた血管石灰化の形態学的特徴とステント留置への影響

抄録

Calcification of the coronary artery significantly impacts percutaneous coronary intervention (PCI) success and long-term outcomes. This study developed a novel quadrant calcium score (QCS) using optical coherence tomography (OCT) to comprehensively assess the calcification distribution and eccentricity. By analyzing four-quadrant coronary imaging，researchers found that calcification predominantly localizes in single or two quadrants (76.7%) , with high eccentricity in 46.7% of cases. The research revealed a strong negative correlation between the eccentricity index and stent expansion (r＝−0.66) . Multi-quadrant highly eccentric calcification emerged as an independent predictor of stent expansion failure (OR 3.2, 95% CI:1.1-9.4) . The newly developed QCS demonstrated superior discriminative performance compared to conventional assessment methods. This quadrant analysis approach enables a more accurate prediction of stent expansion challenges and supports personalized treatment strategy selection, potentially improving PCI procedural outcomes and patient prognosis.