ラグランジュ未定乗数法に基づく血管透過性の推定のためのデータ同化法

（推定値の補正方法の提案）

抄録

In this study, we revealed a cause of overestimation of the permeability coefficient, and proposed a method to correct it. The theoretical solution of a one-dimensional mass diffusion problem with a permeable membrane was dealt to consider the cause of the overestimation. A relational expression between the permeability coefficient and the concentration gradient indicates that the overestimated concentration gradient increases the error of the permeability coefficient than the underestimated one when they are comparable. The treatment for this overestimation of the permeability coefficient is discussed in the presentation.