加圧式定量噴霧式吸入器(ｐMDI)用自動噴霧デバイスの継続利用による吸入状況の変化

抄録

One of the problems with using PMIs for inhalation treatment is that there are cases in which patients fail to spray a dose at proper timing. In order to solve this problem, for this research, we developed an automatic spraying device (automatic inhaler) that automatically sprays according to the monitored timing and studied the changes in inhalation status under the continuous use of the device.As a result, because the subjects were not required to spray a dose at proper timing with the use of the automatic device, we could approximate the inhalation speed and volume to the desired values. Also, as some of the subjects learned the proper timing through the continuous use of the device, they became able to spray a dose at the proper timing even without using the device. However, because the device requires a medicine bottle to be pushed a force of over 50N to spray, even though the subjects started to push their bottles with perfect timing, some ended up missing the optimal timing to spray.