抄録
Nailfold video capillaroscopy (NVC) examines the micro vascular structure noninvasively and aids in the diagnosis of capillary disease, such as Raynaud's phenomenon. We developed high speed digital video capillaroscopy which is composed of high speed digital video camera, deep-focus lens, metal halide light source, and light collecting adaptor. We obtained sequential images of nailfold microcirculation loop with much higher temporal resolution than conventional capillaroscopy. The high speed digital video capillaroscopy enabled us to evaluate quantitatively both micro vascular structure and red blood cell movement. The objects of this study are to measure the radius distribution of micro vascular by Level Set method and also the red blood cell velocity by tracing plasma gap between blood cells.