皮質骨の微細構造と骨ミネラル密度がその力学的特性に及ぼす影響

抄録

CT technology has been widely used in bone studies with high resolution and the ability to observe the microstructure of a material without damage to the sample. The high-resolution CT can accurately obtain the internal microstructure parameters of the cortical bone. Therefore, this technique can be used to study the influence of the microstructure parameters of cortical bone on its mechanical properties. In this study, 5 bovine specimens with the size of 19mm×3.5mm×1mm are prepared. Cortical porosity, canal diameter, canal separation, number of canal and degree of anisotropy for each sample. By the quasi-static three-point bending test with a rate of 0.1 mm/min, the loading force-displacement curve could be obtained. The following constitutive parameters: elastic modulus, tangent modulus, yield stress, effective plastic strain, yield strain and ultimate stress could be calculated. The effects of bone micro-structure and bone mineral density on the mechanical properties of bone were investigated using multiple linear regression analysis in SPSS (Statistical package of social science) software.