Image Processing based Closed Loop Automated Control System for Cell Bio-Manipulation using LabVIEW and FPGA

抄録

Compare to the conventional contact-type and non contact-type bio-object manipulation methods like gripper, magnetic force or laser field, Multiple Microfluidic Stream-based Manipulation (MMSM) has shown more advantages because it is a bio-compatible, non invasive and multiple scale open space manipulation. This method uses small and controllable amount of fluid to achieve various kinds of operations on cells such as moving, rotating or holding and also for micro assembly of bio-objects. In previous works, performances of this bio-manipulation method could not be fully exploited due to the limited proposed automated system. A new image processing closed control loop is proposed for a Lab on a chip system to detect and manipulate cells efficiently.