The Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec)
Online ISSN : 2424-3124
2019
Session ID : 1A1-T01
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Fluid-packed Pressure Homogenizing Cell Membrane Perforator and Photooxidative Cell Membrane Perforating System for Cell Groups
*Mizuki FUJIWARATakahiro NAKAMURAItsuki KAMATATakashi Kei SAITO
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Abstract

Our photochemical cell membrane perforation method is new approach for mass cell processing, eg. cell therapy or regenerative medicine. The method requires homogeneous control of cell attaching pressure of nano brush shaped cell membrane perforator which contains photosensitizer, but it was hard because almost the cell size are micrometer scale and its structure is weak. Recently we made the fluid-packed perforator to homogenize the applying pressure, based on Pascal’s principle. This perforator has flexible surface which can adopt variations of cell layer on culture dishes, but fluid-packed process was hard. In this research, we will report the new fluid-packed perforator with stable process.

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© 2019 The Japan Society of Mechanical Engineers
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