Host: The Japan Society of Mechanical Engineers
Name : [in Japanese]
Date : June 05, 2019 - June 08, 2019
Cell–cell interaction is a vital component of human life activity. Obstacle existing in cell interaction can lead to many diseases and how two or more cells interaction can directly influence the migration, proliferation of cells, so different numbers of cells are required to be fixed. The development of microfluidic device using the hydrodynamic structure and the application of controllable closed fluidic environment provide a good direction for us. In this paper, we present the microfluidic device which could achieve the capture of double cells or triple cells respectively for cell-cell interaction analysis by changing the microfluidic structure with the simple and common approach. With experimental verification, the devices using the passive fluid force can all achieve the high efficiency and the high throughput. We envision that the efficient microfluidic device can be applied in more biological research on cell-cell interaction.
