タンパク質Ｘ線結晶構造解析実験のための試料交換システムの高速化

抄録

To solve three dimensional structures of protein is important for not only basic science, but also pharmaceutical industries. One of the most popular methods for protein structure analysis is X-ray crystallography. A sample exchange system is a key technology for high-throughput X-ray experiments. Structural Biology Research Center in KEK has developed and operated sample exchange system PAM at beamline 5A, 17A, AR-NW12A and AR-NE3A, and PAM-HC at beamline 1A of Photon Factory (PF). Because time required for data acquisition has become shorter recently, faster sample exchange system is desired. In this paper, we introduce newly-developed sample exchange system. Moreover, preliminary experimental results of sample position calibration in a liquid nitrogen dewar of new system is described.