アルギン酸ファイバーを用いた栄養状態反転がん細胞凝集体作成デバイス

抄録

Recent research has revealed that cancer cells far from blood vessels present in hypotrophic in tumor and they deeply involve malignant transformation such as metastasis and recurrence. In this study, we develop a device to make it possible to observe such cells present in the hypotrophic region in vitro. The device supplies nutrients from the inside of the cell aggregate using alginate fibers and can form regions with different nutritional states inside the three-dimensional cell aggregate.