生分解性材料を用いたマイクロ構造体作製の研究

抄録

For the donor scarcity problem, there are many Tissue Engineering studies. We fabricated toroidal cell structures inside a microflPA000354941-310uidic device for tissue engineering applications. A photo-crosslinkable biodegradable hydrogel gelatin methacrylate (GelMA) was employed to encapsulate biological cells for assembling cell structures. stabilizeing the unstable GelMA manufacturing method,we review the manufacturing method and searched for a method that can be stavly produced. So changing the diakysis method, It was possible to prepare GelMA which is suitable as a cell culture medium. RLC-18 cells grow up on the micro structure. When RLC-18 cells grow up, GelMA is gradually reduced.