逆ピンセット構造の培養筋による駆動の実証とそのモデル化

抄録

Bioactuators, which use muscle tissue or cells as drive sources, have been attracting attention as actuators with unconventional characteristics. It is important for the control of bioactuators to develop a mathematical model, but, to the best of our knowledge, no model has been reported to suppose the application to devices. In this study, Hill's four-element model was applied to tissue-engineered muscles constructed by culturing mouse myoblasts C2C12 in collagen gel. The muscles were isometrically contracted and the maximum contractile force was about 2.9 mN. Then, the parameters of the model were determined from the results of the regression analysis. In addition, the reverse tweezers structure was driven by the muscle. The tip of the reverse tweezers was displaced up to 0.6 mm by muscle contractions. As a next step, we will control the reverse tweezers structure by applying the model.