Host: The Japan Society of Mechanical Engineers
Name : [in Japanese]
Date : June 01, 2022 - June 04, 2022
In this report, we evaluated the mechanical properties of liposomes by the micropipette aspiration method for the development of molecular robots. We prepared liposomes with the W/O emulsion method and aspirated them on the micropipette using negative pressure generated by the difference of the water head. We measured the deformation length of a liposome which was aspirated in the micropipette with the microscopic image. The deformation was applied to the viscoelastic model. In the result, we derived Young’s modulus (E0 = 416 Pa and E∞ = 57.3 Pa) and viscosity (μ = 120.4 Ns/μm). These parameters were smaller than these of cells. We considered that the result was due to the lack of cytoskeleton which keeps the form of cells of the living things. In the future, we will try to measure more liposomes and derive more accurate parameters.
