Abstract
Male rats of the Wistar strain, weighing about 42g were fed 70% casein diet with or without vitamin B6. Growth rate of rats fed vitamin B6 dificient diet was markedly retarded. Liver enlargement and fat deposition, which resulted from increases in triglyceride and cholesterol, were observed in the vitamin B6 deficient rats. Liver weights and fatty acid compositions in the normal rat livers were changed during 19 hour starvation, whereas those of the deficient rat livers were not changed during the same starvation period. Impaired oxidation of fatty acids in the deficient rat will be suggested. Fatty acid compositions of carcass lipid were determined and an increase in arachidonic acid content in the deficient rat was remarkable.
