Abstract
Effects of hydrocortisone on the formation of sucrase-isomaltase complex during development were investigated in rat intestinal mucosa using Sephadex G-200 column chromatography. On 11th, 12th and 13th days after birth, suckling rats were injected with hydrocortisone intraperitoneally. Disaccharidases activities of rat intestinal mucosal homogenates from 15-day old rats were significantly increased in 15-day old rats treated with hydrocortisone. Profiles of Sephadex G-200 column chromatography of papain solubilized intestinal disaccharidases from 15-day old rats, 15-day old rats injected with hydrocortisone and adult rats revealed that hydrocortisone stimulated the formation and modification of sucrase-isomaltase complex.
