Abstract
The usefulness of a soluble dietary fiber (0.6g carrageenan extracted from red algae) and protein (0.9g casein) mixture (FPM) for metabolic control was examined in 9 patients with non-insulindependent diabetes mellitus. FPM dissolved in 200ml of hot water was administered to each patient twice daily for 2 weeks. The body weight, plasma HbAlc and Apo B levels after treatment for 2 weeks were significantly lower than those before the treatment. Mixed meal loading without FPM after the 2-week treatment produced a less marked increase in plasma glucose and a higher increase in serum insulin in comparison with those before the treatment. The intake of FPM caused a feeling of stomach fullness in spite of calory restriction as a dietary regimen for the treatment of diabetes mellitus. These results suggest the usefulness of this fiber-protein mixture for metabolic control and prolongation of the feeling of stomach fullness in patients with non-insulin-dependent diabetes.
