筋萎縮性側索硬化症と多系統萎縮症　―睡眠関連呼吸障害を中心に―

抄録

I review diagnosis and treatments against sleep–related breathing disorder (SRBD) observed in neuromuscular diseases including amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). SRBD includes sleep apnea syndrome, nocturnal stridor, hypoventilation, and central respiratory disturbance. These conditions cause frequent awakening, nocturnal pollakiuria, morning headache, and hypersomnia. Clinical examination followed in selected patients by nocturnal saturation monitoring and polysomnography is essential for correct diagnosis and treatments.