神経治療学
Online ISSN : 2189-7824
Print ISSN : 0916-8443
ISSN-L : 2189-7824
特集 神経疾患の栄養療法―基礎から最新情報まで―
多系統萎縮症の栄養療法
國枝 顕二郎下畑 享良
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ジャーナル フリー

2022 年 39 巻 1 号 p. 31-33

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Nutritional impairment in multiple system atrophy (MSA) can be divided into early and advanced stages. In the early stage, nutritional impairment due to dysphagia can develop. In the advanced stage, body fat could accumulate after the introduction of a ventilator or the placement of a gastrostomy. Nutritional impairment may be progressive in MSA patients, even if body weight is maintained. The serum albumin level is a useful indicator of nutritional status. Leptin resistance due to autonomic neuropathy may be related to the accumulation of body fat. In the early stages, sufficient nutrition should be administered to prevent the progression of nutritional disorders. In the advanced stage, the amount of administered energy is reduced to prevent fat accumulation. Further research is needed to establish the evidence for the nutritional management of MSA.

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