認知症有病率減少についての考察：石川健康長寿プロジェクトから

抄録

In May 2024, a decline in the prevalence of dementia in Japan was reported, which has become a hot topic. This decline is thought to be attributable to factors such as improved educational levels and better management of cardiovascular risk factors. The Lancet Standing Committee has provided 14 evidence–based recommendations regarding lifestyle behaviors and interventions. Our study also showed that diabetes prevention and treatment, as well as exercise and nutritional guidance, may be effective for prevention of dementia. Furthermore, brain imaging studies revealed that abnormal glucose metabolism is associated with hippocampal atrophy, which plays a key role in memory and learning. As more people engage in dementia prevention measures, the prevalence of dementia in Japan is expected to continue decreasing.