日本口腔診断学会雑誌
Online ISSN : 2188-2843
Print ISSN : 0914-9694
ISSN-L : 0914-9694
臨床報告
アンギオテンシンⅡ受容体拮抗薬が誘因と推察された頰部,下唇に発生した血管性浮腫の1例
篠原 治征杉浦 正
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ジャーナル フリー

2019 年 32 巻 2 号 p. 137-141

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Angioedema (AE) occurs due to various factors and may be seen as a side effect of drugs. Many causative drugs have been reported, and many antihypertensive drugs are reported to be angiotensin converting enzyme (ACE) inhibitors, but angiotensin Ⅱ receptor antagonists (ARB) are rare. We report one case of the cheek and lower lip in which we speculate that AE was induced by ARB. A 62-year-old man was admitted to our department because of swelling of the right cheek and lower lip. In CT, there was no abnormal finding that seemed to cause the swelling of the cheek and lower lip, and uniform soft tissue concentration was observed. Clinically, AE was considered and oral administration of tranexamic acid 300mg/day was started. We speculated that ARB was the causative drug. We asked the internal medicine about drug exchange. And the drug was discontinued. Swelling of the right cheek and lower lip had disappeared at the time of re-examination 2 weeks later, and recurrence of AE has not been observed since the drug discontinuation.
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