日本口腔診断学会雑誌
Online ISSN : 2188-2843
Print ISSN : 0914-9694
ISSN-L : 0914-9694
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生検後に消失した下顎骨に生じた成人型ランゲルハンス細胞組織球症の1例
秋森 俊行上田 大佑髙田 まゆこ椛田 晃成宮薗 利朗宮脇 昭彦
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2021 年 35 巻 1 号 p. 66-70

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Langerhans cell histiocytosis (LCH) is a rare condition that is common in children but rarely occurs in adults. Although the treatment plan for LCH differs according to its clinical form, there are some forms for which no therapy has been established. We report a case of LCH involving the mandible of an adult patient in whom the lesion disappeared after a biopsy specimen was obtained for histopathological examination. A 33-year-old man presented to our department with a chief complaint of pain in the left mandibular molar region. Computed tomography (CT) revealed a translucency at a site continuous with the roots of the tooth. Histopathological examination of the biopsy specimen confirmed LCH. 19 months after the biopsy, CT showed bone formation at the biopsy site. Although there is no established treatment for LCH in the oral and maxillofacial region, it may disappear following surgical manipulation such as biopsy, and spontaneous resolution may be expected during follow-up of the patient after biopsy.
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