抄録
Langerhans cell histiocytosis （LCH） is an inflammatory neoplasm of myeloid origin characterized by the accumulation of CD1a/CD207 dendritic cells. Recently, the BRAFV600E mutation has been reported in half of patients with LCH, and BRAFV600E expression was associated with increased risk of recurrence. This report presents two pediatric cases with LCH affecting the right posterior mandible. Both were successfully treated with intralesional injection of dexamethasone （6mg） in one single session. Complete recovery was confirmed approximately 4-5 years after injection. Intralesional corticosteroid is a less invasive alternative to the classical surgical treatment.
