キチン・キトサンに関する研究

―その6．ハイドロキシアパタイト含有キチン・キトサンフィルムの引張強さに及ぼす中和材の濃度について―

抄録

Chitosan is absorbed in vivo. Chitosan sol is produced by dissolving chitosan in a solution of malic acid. A chitosan film is formed by neutralization with the sodium polyphosphate solution, and then gelatinizes. The effects of the concentration of sodium polyphosphate solution on the tensile strength and elongation of chitosan film were examined. The chitosan sol dissolved in malic acid could not be neutralized with 2% sodium polyphosphate solution. By decreasing the concentration of sodium polyphosphate solution, the pH value of the neutralized chitosan decreased. By increasing the concentration of sodium polyphosphate solution, the tensile strength and elongation of chitosan film prepared with malic acid increased. By increasing the soaking period in physiological saline solution, the tensile strength and elongation of chitosan film prepared with malic acid decreased. When chitosan fibers were observed, the tensile strength decreased after the chitosan film was soaked. The tensile strength of chitosan film prepared with malic acid, followed by neutralization in a solution with a high concentration of sodium polyphosphate, showed higher tensile strength.