歯科薬物療法
Online ISSN : 1884-4928
Print ISSN : 0288-1012
ISSN-L : 0288-1012
塩酸レナンピシリン (タカシリン錠) の吸収におよぼす健胃散併用の影響度
埜口 五十雄佐藤 泰則安藤 俊史黒川 英人高橋 雅幸金子 徹上園 善子
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1991 年 10 巻 2 号 p. 185-189

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In daily clinical practice, antacids have been shown to affect and for interfere with the absorption of antimicrobial agents in many cases. Since Lenampicillin is often used for infection in oral surgery, it is very impotant to study the effects of antacids on Lenampicillin's absorption.
It appears that there is no significance difference of Cmax and AUC of the group given Lenampicillin and the group given Lenampicillin plus antacids. There also seems to be no difference in blood concentration between the two groups, which means that the absorption of Lenampicillin is not affected even by antacids in combined dosage.
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© 日本歯科薬物療法学会
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