抄録
This has been a report of headache as side effects after administration of antimicrobial agent. We encountered two cases. Case 1 was diagnosed as having chronic mandibular osteomyelitis. Cefteram pivoxil (CFTM-PI) was administrated to this patient in three 200 mg doses daily, one dose after each meal. The patient complained of a headache 2 to 3 hours after receiving the initial dose of 200mg.
Case 2 was diagnosed as possibly having postoperative infection. Roxithromycin (RU28965) was given in two 150 mg doses daily after breakfast and dinner for 4 days. This patient complained of a headache after the initial dose of 150mg, and it lasted for 4 days.
In these two cases, appearance of the headache occurred at about the time of maximum serum level.
We report these cases, because there have been few reports of headache as a side effect of these antibiotics.
