歯科薬物療法
Online ISSN : 1884-4928
Print ISSN : 0288-1012
ISSN-L : 0288-1012
ピペラシリン (PIPC) の使用によりアレルギー (発熱) を生じた2例
森川 雅之岩田 雅裕小山 茂樹高木 慎西嶋 克巳
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1993 年 12 巻 2 号 p. 130-134

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All medicines have some side effects. Medicines are used when the effect is more than the side effect.
In the cases of antibiotics, their effect for infection is very large, so usually, in consideration of the effect, the side effect does not become a subject of discussion. But drug fever is one side effect that may take a turn for the worse, if we mishandle it.
The fever in administration of medicine is called drug fever, universally it occurs due to the method of administration, physiological function of medicine, change of system for regulation of body temperature, factor of patient, and allergy.
This has been a report of drug fever as side effect, allergy, after administration of piperacillin sodium.
In the course of treatment for infection, body temperature became normal, occasionally rising again. As fever is the main symptom of infection, judgment of fever, whether it is caused by a drug or resistant bacteria, is very difficult.
Clinically, in the case of an unknown fever, according to the circumstances, not only catching the situation of patient but suspending the administration of medicine is necessary.
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