歯科薬物療法
Online ISSN : 1884-4928
Print ISSN : 0288-1012
ISSN-L : 0288-1012
薬物療法が奏効した慢性肥厚性口腔カンジダ症の1例
水川 展吉西嶋 寛三好 憲裕森 貴幸西嶋 克巳
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1995 年 14 巻 2 号 p. 138-140

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Chronic hyperplastic oral candidiasis is a disease which features the development of white lesions resembling leukoplakia. Although there have been a number of reports on this disease from foreign countries, it has rarely been reported in Japan.
This disease is basically treated with antifungal agents. However, it often requires longterm therapy, and epithelial dysplasia may remain in some cases, even after the fungus has been eliminated. Moreover, since malignant transformation has been reported, surgical excision should be performed when the disease has run an excessively long course.
The experience with a patient, who was histopathologically diagnosed as having chronic hyperplastic oral candidiasis is reported. A summary of this case is presented along with a reviw of the literature.
A 67-year-old man visited our clinic with the chief complaint of bilateral buccal mucosal pain while eating. After making a clinical diagnosis of lichen planus, biopsy was performed, resulting in a histopathological diagnosis of chronic hyperplastic oral candidiasis. With antifungal therapy, the lesions disappeared within three months after diagnosis at our clinic. The patient has not relapsed up to the present (January 31, 1995) .
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