抄録
“Inteban ointment”contained a non steroidal anti-inflammatory agent of indomethacin, was used to 36 patients of mandibular arthrosis without any other treatment.
The application method of the ointment was that 5 to 8g of them for one day were divided to 4 times, and rubbed in tempolo-mandibular joint region after meals and before sleep.
The evaluation of the clinical efficacy was judged by score method that each symptoms of mandibular arthrosis were given the standardized score by the severity, compared and analysed with statistically the score of first day, 7th day and 14th day from the start of application.
The results obtained were as follows:
1. Average score of the first day 10.58 was improved to 6.39 at 14th day, showing a significant difference (p<0.001, t-test) .
2. The symptoms show the remarkable improvements were oppressive pain on tempolomandibular joint region, and spontaneous pain at mandibular movement.
3. Side-effect was not recognized in this series.
