歯科薬物療法
Online ISSN : 1884-4928
Print ISSN : 0288-1012
ISSN-L : 0288-1012
高血圧患者の歯科治療時におけるCa++拮抗剤“nifedipine”の応用
中村 仁也塩谷 泰宏伊藤 努山城 三喜子古屋 英毅
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1983 年 2 巻 1 号 p. 24-28

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In the dental treatment of hypertensive patients, we applied nifedipine, which reliable and mild effects are expectable, and obtained good results.
The subjects used are 10 hypertensive patients categorized as the stage I and II of WHO classification who visited our hospital for tooth extraction. The ages of patients ranged from 54 to 76 years old.
Local anesthesia with 2% lidocaine containing 1/80, 000 epinephrine was applied 20 min after sublingual administration of 10mg of nifedipine. Then, 10 min later, blood pressure, mean blood pressure and pulse rate were measured.
Both systolic and diastolic pressures started to decline 5 min after the administration of nifedipine, reached the minimum level after 20 min and stayed at that level until 60 min after the administration.
Pressor effect due to the local anesthesia and tooth extraction was mild, and hemodynamics was kept stable. Also, neither dizziness nor body sway was observed.
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© 日本歯科薬物療法学会
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